Endocrine Abstracts

The molecular basis of parathyroid tumorigenesis has increased greatly over the last years and the variety of described abnormalities suggests different genetic defects leading to dysfunction of parathyroid cells. Using a combined approach based on two-dimensional electrophoresis (2DE) and mass spectrometry (MS) we performed a comparative proteome analysis to examine the global changes of parathyroid adenoma tissues protein profile with respect to the normal parathyroid tissue...

Background: Riedel’s thyroiditis (RT) is a rare thyroid disease. Clinical and citological differential diagnosis with thyroid malignancy is difficult pre-operatively and often only pathological report may confirm the diagnosis.Methods: We report a case of a 72-year-old Italian woman with a known history of goiter, which showed a rapid increase in size at ultrasound check, suggesting malignancy. Based on non-diagnostic cytology (Thy 1), a total thyro...